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Year : 2019  |  Volume : 10  |  Issue : 3  |  Page : 105-111

A radiographic study on craniofacial morphology and dental development in the Jordanian patients with ß-thalassemia major

1 Orthodontic Department, Al-Bashir Hospital, Amman, Jordan
2 Oral Medicine Department, Al-Bashir Hospital, Amman, Jordan
3 Pediatric dental Department, Al-Bashir Hospital, Amman, Jordan

Correspondence Address:
Juman Mohammad Al-zaben
Department of Dental, Orthodontic Clinic, Al-Bashir Hospital, P. O. Box: Amman
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijor.ijor_13_19

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Objective of the Study: This study aimed to study the cephalometric features of Jordanian patients diagnosed with ß-thalassemia major and compare their dental development with their chronological age. Subjects and Methods: This was a case–control study. Lateral cephalometric radiographs of 27 thalassemia patients and controls (matched for age and ethnic origin) were analyzed and compared. Panoramic radiographs of 18 thalassemia patients were analyzed by the Demirjian system to assess their dental development and compare with their chronological age using t-test, with P < 0.05 set as the level of statistical significance. Results: Thalassemia patients exhibited a highly significant difference, compared to the controls, in sagittal relationship (ANB), mandibular plane inclination (MxP/MnP), anterior rotation of the maxilla (SN/Mxp), the ratio of posterior to anterior face height, and the upper incisors' distance to the maxillary base (P < 0.005). Prominent upper and lower lips (P < 0.001) and an acute nasolabial angle (P < 0.05) were evident in thalassemia patients compared to controls. Thalassemia patients had a delay in dental development with advancing age. Furthermore, there was a statistically significant correlation (P < 0.001) between the extent of this delay and chronological age, which indicates that the delay increases, as the patient gets older. Conclusions: Jordanian ß-thalassemia major patients have a Class II skeletal pattern, a prominent vertical growth direction of the mandible, protruded upper and lower lips, and proclined upper incisors. Furthermore, they have a delay in dental development with advancing age.

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